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Key Points Oxyntomodulin and peptide tyrosine–tyrosine (PYY) are gut peptides that are released postprandially Oxyntomodulin and PYY act as satiety signals via effects on appetite centers such as the hypothalamus and brainstem Exogenous administration of oxyntomodulin or PYY 3–36 reduces energy intake, adiposity and body weight in animals Several studies suggest that drug therapy based on these hormones could be an effective treatment for human obesity This is a preview of subscription content, access via your institution Access options Subscribe to this journal Receive 12 print issues and online access $189.00 per year only $15.75 per issue Buy this article Purchase on SpringerLink Instant access to the full article PDF
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The aim of this review is to explore and propose possible mechanisms through which GLP-1RAs may contribute to gallbladder disease and to evaluate the current clinical evidence on the incidence and severity of gallbladder-related adverse events in patients undergoing GLP-1RAs therapy
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